Acclaim HILIC-10 Columns

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  • 技术参数
  • 相关原理
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The Thermo Scientific Acclaim HILIC-10 column is designed for separating highly hydrophilic molecules by hydrophilic interaction liquid chromatography (HILIC). This column is suited for use in a broad range of applications, including separation of hydrophilic drugs and drug metabolites.

  • Retains highly polar molecules that are not retained by reversed-phase chromatography

  • Unique selectivity, complementary to reversed-phase columns

  • Hydrolytically stable

  • Rugged column packing

  • Broad application range

The advantage of the Acclaim HILIC-10 phase is the compatibility with up to 20% aqueous mobile phase, while maintaining affinity for polar analytes. Acclaim HILIC-10 columns are available in 3 μm particle size. A variety of column formats are available: 4.6 × 150 mm, for high-throughput routine analysis; 3.0 × 150 mm, for high-throughput analysis with reduced solvent consumption; and 2.1 × 150 mm, for LC-MS analysis.


Acclaim Mixed-Mode HILIC-1 Columns  Specifications
Particle size:5 µm
Base silica:Spherical, high-purity
Pore size:120 Å
Surface area:300 m2/g
Column chemistry:Proprietary alkyl diol


    Analytical Columns
    Acclaim Mixed-Mode HILIC-1, 3µm Analytical (3.0 x 150mm)070090
    Acclaim Mixed-Mode HILIC-1, 3µm Analytical (3.0 x 50mm)071912
    Acclaim Mixed-Mode HILIC-1, 3µm Analytical (2.1 x 150mm)070091
    Acclaim Mixed-Mode HILIC-1, 5 µm (4.6 x 150 mm)066843
    Acclaim Mixed-Mode HILIC-1, 5µm (4.6 x 250 mm)066844
    Acclaim Mixed-Mode HILIC-1, 5 µm (2.1 x 150 mm)066847
    Guard Columns
    Acclaim Mixed-Mode HILIC-1, 5 µm Guard Cartrdiges, (4.6 x 10 mm), 2 ea (use V-2 Holder)069706
    Acclaim Mixed-Mode HILIC-1, 5µm Guards (3 x 10mm), 2ea, requires holder 069580071913
    Acclaim Mixed-Mode HILIC-1, 5µm, Guards (2.1 x 10mm), 2 ea; requires holder 069580069694
    Acclaim SST Guard Cartridge Holder V-2069580
    Acclaim Guard Kit (Holder and coupler) V-2069707
    Guard to Analytical Column Coupler V-2074188